The Relationship of Circumcision With Clinical Tumor Staging of Penile Cancer

  • Marco Bandini
  • Philippe E. Spiess
  • Yao Zhu
  • Antonio A. Ornellas
  • Benjamin A. Ayres
  • Oliver W. Hakenberg
  • Friederike Haidl
  • Filippo Pederzoli
  • Giuseppe Basile
  • Alberto Briganti
  • Francesco Montorsi
  • Juan Chipollini
  • Mounsif Azizi
  • Gert De Meerleer
  • Oscar R. Brouwer
  • Maarten Albersen
  • Andrea Necchi
  •  Peter A. S. Johnstone
Keywords: Penile cancer, , cancer staging, circumcision


In this report, we look at the relationship between prior circumcision and presenting stage of penile cancer. We
performed an analysis of an international, multicenter database of 1254 penile cancer patients diagnosed from 1980
to 2019 in the United States, Europe, Brazil, and China, and analyzed the relationship between circumcision and
presenting T and N stage. A total of 710 patients met the inclusion criteria and were statistically analyzed. We found
that uncircumcised men with locally advanced tumors (T3–T4) had significantly higher risk of lymph node metastasis
compared with circumcised men.

Author Biographies

Dr Hakenberg

Dr Chipollini


How to Cite
Bandini, M., Spiess, P. E., Zhu, Y., Ornellas, A. A., Ayres, B. A., Hakenberg, O. W., Haidl, F., Pederzoli, F., Basile, G., Briganti, A., Montorsi, F., Chipollini, J., Azizi, M., De Meerleer, G., Brouwer, O. R., Albersen, M., Necchi, A., & Johnstone, PeterA.S. (2022). The Relationship of Circumcision With Clinical Tumor Staging of Penile Cancer. Société Internationale d’Urologie Journal, 3(2), 102–107.
Brief Communication